Sustained efficacy of incobotulinumtoxinA in upper-limb post-stroke spasticity: A post hoc analysis
نویسندگان
چکیده
منابع مشابه
Randomized, placebo‐controlled trial of incobotulinumtoxina for upper‐limb post‐stroke spasticity
INTRODUCTION Efficacy and safety of incobotulinumtoxinA in post-stroke upper-limb spasticity were studied. METHODS Subjects randomized 2:1 to incobotulinumtoxinA (fixed dose 400 U) or placebo, with fixed doses for the primary target clinical pattern (PTCP; flexed elbow, 200 U; flexed wrist, 150 U; clenched fist, 100 U). Doses for non-primary patterns were flexible within predefined ranges. ...
متن کاملcomparing the efficacy of botulinum toxin with tizanidine in upper limb post stroke spasticity.
background: this study evaluated the efficacy of focal intramuscular injection of botulinum (bont) toxin type a in comparison with oral tizanidine (tzd) in treatment of post-stroke upper limb spasticity. methods: this was a double-blinded randomized clinical trial that recruited 68 patients with post-stroke upper limb spasticity. thirty-four patients received bont (dysport(®)) injections in aff...
متن کاملComparing the efficacy of botulinum toxin with tizanidine in upper limb post stroke spasticity
BACKGROUND This study evaluated the efficacy of focal intramuscular injection of botulinum (BoNT) toxin type A in comparison with oral tizanidine (TZD) in treatment of post-stroke upper limb spasticity. METHODS This was a double-blinded randomized clinical trial that recruited 68 patients with post-stroke upper limb spasticity. Thirty-four patients received BoNT (Dysport(®)) injections in aff...
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BACKGROUND Limited empirical information exists regarding botulinum toxin-A injector decision-making practices for adult upper limb post-stroke spasticity. The design of most studies prevents such an assessment, as injection sites and dosage are mandated by researcher protocols. This contrasts to usual injector practices, where individualized decision-making is the standard of care. DESIGN Se...
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Botulinum toxin is significantly associated with decreased spasticity, increased range of motion and improved upper extremity function. Botulinum toxin in combination with electrical stimulation improves upper extremity function. Deinnervation of the subscapularis muscle using botulinum toxin may reduce shoulder pain and improve passive range of motion, more so than deinervation of the pectoral...
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ژورنال
عنوان ژورنال: Toxicon
سال: 2021
ISSN: 0041-0101
DOI: 10.1016/j.toxicon.2020.11.416